Investigadores identifican molécula con potencial para reducir la inflamación y el daño cerebral tras un ictus isquémico
Una investigación del CSIC identificó a la cortistatina como una molécula con potencial para reducir la inflamación y el daño cerebral tras un ictus isquémico.
El estudio fue liderado por el Instituto de Parasitología y Biomedicina López-Neyra (IPBLN-CSIC), junto al Hospital Universitario de Lausanne, en Suiza.
Los hallazgos, publicados en Journal of Biomedical Science, combinan análisis de pacientes con modelos animales para evaluar el papel de esta molécula.
Disminuye tras el ictus y se relaciona con la gravedad
Los investigadores comprobaron que los niveles de cortistatina disminuyen significativamente después de un ictus en pacientes y modelos animales.
Además, observaron que esta reducción se asocia con cuadros clínicos más graves y una mayor lesión cerebral.
Según el estudio, la ausencia de cortistatina empeora la respuesta del cerebro frente a la falta de riego sanguíneo.
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